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This approach reduces stress and discomfort for the animals while maintaining efficacy

Each group used different tools: 1- The VR Group navigated existing situations during Understand and Frame, 2- The AI Group used UrbanistAI to visualise scenarios in Imagine & Ideate, and 3- The non-digital Group worked with plastic construction bricks and printed images

In in vitro cell experiments using 3T3L1 preadipocytes as a model, treatment with NNMTi significantly reduced preadipocyte differentiation efficiency and markedly downregulated the expression of adipocyte markers (such as PPAR and C/EBP) in a dosedependent manner

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NAD plays a central role in cellular repair and mitochondrial function