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10.2174/1568026615666150703115919 131 JangS.KimK
B12 is a co-substrate of various cell reactions involved in methylation synthesis of nucleic acid and neurotransmitters
They: Produce collagen Organize extracellular matrix Restore tensile structure In experimental tendon transection models, BPC-157 has been associated with: Increased fibroblast density Enhanced migration into injury site Accelerated granulation tissue formation Proposed signalling involvement includes: FAK (Focal Adhesion Kinase) activation ERK1/2 signalling Src pathway modulation FAK signalling is particularly important because it regulates: Cell adhesion Cytoskeletal reorganization Migration along collagen scaffolds Tendon strength depends not just on collagen quantity but alignment
For those with more severe deficiencies or absorption problems, B12 injections may be prescribed
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