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Mechanistic studies of the plant GCL demonstrated that reversible disulfide bond formation alters catalytic activity with the oxidized protein more active than the reduced protein (Jez et al., Subsequent crystallographic and functional studies established the molecular basis for this thiol-based redox-switch

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Allyl isothiocyanate (AITC) induces stomatal closure in Arabidopsis

In this paper, we will summarize the results of the Phase 3 study that led to the approval of L-glutamine for treating SCD and discuss its assumed mechanisms of action