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Each of the experiments was performed at least three times

In another RDP study on 20 patients with CVI, Pycnogenol supplementation (300 mg/day for two months) reduced venous pressure significantly by 9.8 and 8.3% (right and left legs, respectively) compared to baseline ( group compared to a reduction of 12.6% in the placebo group

Specifically, heart attack rate was 44% lower, stroke rate was 63% lower, rate of cardiac death was 45% lower, and rate of peripheral artery disease requiring amputation was 43% lower with omega-3 fatty acids than placebo (corn oil)

J Am Soc Nephrol 24:20342043

And if they have two versions, they got one from their mom and one from their dad, they live on average two years longer than people that don't have that SNP