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DNAMAN software was used to perform multiple alignments

Because it is not sustainable to feed fish with fish, our findings have important implications for expanding the global production of HSB that are fed low-fishmeal and high-plant ingredient (including SBM) diets

Future research should focus on integrating genetic screening with environmental risk assessment to develop precision medicine strategies for individuals at high risk of both conditions

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Future randomised controlled trials should specifically evaluate the effectiveness of novel AOMs for long-term weight management in older adults with obesity, carefully considering the impact on body composition and functional ability, as well as health economics