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The disruption of endothelial homeostasis results in compromised perfusion of skeletal muscle, a decrease in capillary density, and inadequate delivery of oxygen and nutrients to muscle fibers, ultimately leading to anabolic resistance and muscular atrophy (20)

As demonstrated in Table 2 , dietary supplements such as S-Adenosylmethionine, acetylcarnitine, creatine, and amino acids have been investigated (157, 158)

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Structural and metabolic changes in Atp7b/ mouse liver and potential for new interventions in Wilsons disease

263 Fatty acid metabolism maintains normal energy metabolism and life activities by enhancing lipid synthesis, storage, and catabolism