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In 50% of cases of idiopathic non-obstructive azoospermia (INOA), it has an unidentified genetic basis, and this suggests that the polymorphism of genes in autosomal chromosomes may also play an important role in spermatogenesis [85]

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Inositol plays a crucial role in cellular signaling and helps regulate both insulin and glucose metabolism [7]

46 While ID typically causes microcytosis and vitamin B12 and folate deficiencies cause macrocytosis, the co-occurrence of these deficiencies may obscure clinical features and complicate diagnosis, leading to underestimation of the prevalence of iron, vitamin B12 and folate deficiencies

A small number of observational studies have examined selenium status and male fertility or sexual function, with mixed findings