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mucuso (25, 50, and 100 mg/kg) caused a significant increase [ F (5, 54) = 1,369

Meanwhile, ROS attack intracellular proteins, resulting in the abnormal function of many proteins involved in the synthesis, transport and regulation of thyroid hormones

Optimal neuroprotection is observed at ~10 mM, with concentrations below this threshold insufficient to alleviate the metabolic crisis associated with cerebral ischemia (160)

Fluoride exposure can lead to hypothyroidism, particularly detrimental during fetal and early developmental stages affecting IQ, brain, and hearing development

Protein isolation and western blotting For standard western blotting, tissues were lysed in RIPA buffer and extracted protein content was determined using the BCA protein assay (Sigma, St