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FIGURE 4 Development of Ketosteroid Isomerase Activity in the Glutathione Transferase Structure The discovery of human GST A3-3 (HsaGST A3-3) and its association with steroidogenic tissues (Johansson and Mannervik, 2001) prompted the search for mammalian orthologs with similar outstanding catalytic efficiency

the system requires a team of micronutrients to function effectively

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Increased consumption of antioxidants was also reported for other members of the nonenzymatic antioxidant system, including -tocopherol and ascorbic acid (35, 86)

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