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People exposed to high pollution, stress, or irregular sleep patterns

The difficulty is that the report doesnt describe the result as presumptive

These include modulations in gene expression, stimulation of the endocannabinoid system, and action on the central nervous system

Jin Q, Cirelli JA, Park CH, et al

The glucagon-like peptide 1 analogue Exendin-4 attenuates the nicotine-induced locomotor stimulation, accumbal dopamine release, conditioned place preference as well as the expression of locomotor sensitization in mice