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Jan 10, 2026 Tissue repair mechanisms operate through multiple interconnected pathways that rarely respond optimally to single interventions, with injuries activating inflammatory cascades, angiogenic processes, fibroblast proliferation, and extracellular matrix remodeling simultaneously across damaged regions

British Journal of Pharmacology, 179 (14) bph.15327, 3592-3611

Most patients need continued therapy to maintain benefits, though some may attempt supervised discontinuation after achieving significant metabolic improvements

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