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showed that cigarette smoking and nicotine may contribute to pancreatic cancer inflammation by inducing monocyte chemo-attractant protein-1 (MCP-1) and provide a novel insight into a unique role for osteopontin (OPN) in mediating these effects (62)

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Lancet Gastroenterol Hepatol 6:638648 Berkowitz L, Pardo-Roa C, Salazar GA, Salazar-Echegarai F, Miranda JP, Ramrez G, lvarez-Lobos M (2019) Mucosal exposure to cigarette components induces intestinal inflammation and alters antimicrobial response in mice