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GGT is also involved in the transfer of amino acids across cell membranes 103 and metabolism of leukotriene

Supporting this, a study by Krebs (189) demonstrated that Lactobacillus probiotics induced substantial shifts in the gut microbiota of colorectal cancer patients, leading to improved mucosal structure correlated with enhanced colonization by Lactobacillus species

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175 For the PPP enzymes, recent studies have discovered some inhibitors targeting on G6PD, such as NADP + analogs, the competitive inhibitor 6-aminonicotinamide (6-AN), noncompetitive inhibitors epiandrosterone and dehydroepiandrosterone (DHEA) which reduces the availability of NADPH and inhibits the cell growth