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Structurebioactivity relationships of methylxanthines: Trying to make sense of all the promises and the drawbacks

Singh MP, Rai SN, Dubey SK, Pandey AT, Tabassum N, Chaturvedi VK, Singh NB (2022) Biomolecules of mushroom: a recipe of human wellness

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Baltz RH (2018) Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS-derived antibiotics: a perspective

These methods disrupt cellular spatial architecture, overlook cellcell interactions, and perturb the native metabolic state, thus failing to capture the full spatiotemporal heterogeneity of metabolism within the tumor-immune ecosystem