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According to what I think I got from Craddocks incredibly complex EMERGE presentation (which I can no longer find), the models suggest that the main areas of immune system interest in ME/CFS include B and T-cell receptors, TNF-a and transforming growth factor beta (TGF-b)

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Toxin release in response to oxidative stress and programmed cell death in the cyanobacterium Microcystis aeruginosa