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The compound lacks approved human clinical trials, meaning its entire safety profile derives from preclinical animal studies that do not directly translate to human physiology

10.3389/fonc.2018.00248 Summary Keywords apitherapy, anti-inflammation, anticancer, antimicrobial, neuroprotection, wound healing Citation Sadek KM, Shib NA, Taher ES, Rashed F, Shukry M, Atia GA, Taymour N, El-Nablaway M, Ibrahim AM, Ramadan MM, Abdelkader A, Abdo M, Imbrea I, Pet E, Ali LS and Abdeen A (2024) Harnessing the power of bee venom for therapeutic and regenerative medical applications: an updated review

The peptide binds copper through the N-terminal amine, histidine imidazole, and Gly-His amide nitrogen in a square-planar geometry