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Oxygenozone therapy for the treatment of knee osteoarthritis: a systematic review of randomized controlled trials

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These different forms are not interchangeable, and dosing may vary between them

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By suppressing TGF-1 expression and preventing Smad2/3 phosphorylation, luteolin downregulates core ECM components, such as collagen I, fibronectin, and alpha-smooth muscle actin (-SMA), thereby limiting myofibroblast activation and pathological ECM accumulation