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The closest wild relatives were found in South America, but the center of diversity for cultivated forms was in Mexico some 2000 miles to the north

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Whilst snus is still fully legal within its country of origin, Sweden, the EU Tobacco Products Directive is what determines the legal status of snus across the rest of Europe, including the UK

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The combination of lowering glycemic index and increasing the %carb dropped serum urate by -0.27 mg/dL, even adjusting for insulin sensitivity