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[DOI] [PubMed] [Google Scholar] 16.Annual Health Report (2008) Ministry of Health, Sultanate of Oman

Secondary CoQ deficiency is not directly related to the biosynthesis of CoQ, while primary CoQ deficiency results from mutations in genes responsible for CoQ biosynthesis

It is postulated that riboflavin induces NO-mediated vasodilatation, resulting in hypertension relief, through stimulation of the conversion of homocysteine and its subsequent impact on the L-arginine/NO pathway 125 (Fig