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Png CW, Lindn SK, Gilshenan KS, Zoetendal EG, McSweeney CS, Sly LI, et al

An abstract-level assessment led to the exclusion of 852 studies that either lacked quantitative data or did not clearly define exposure parameters, leaving 392 articles for the eligibility evaluation stage

Statistical analysis Prior to statistical analyses, all continuous variables were assessed for normal distribution using the ShapiroWilk test (or KolmogorovSmirnov test for larger sample sizes)

Glutathione and sodium bicarbonate nanoparticles can also decrease mucosal viscosity by alkalizing the airway surface liquid and reducing oxidative crosslinking 91

If the solution becomes cloudy, develops particles, changes color, or develops an unusual smell at any point during the 28-day usage window, discard it immediately