Blood vessels matter because angiogenesis improves oxygen and nutrient delivery to injured tissue, which supports wound, tendon, muscle, and gut lining repair in preclinical models
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Canfield R
The use of hydroxocobalamin became first line due to its low adverse risk profile, rapid onset of action, and ease of use in the prehospital setting
It is a synthetic version of Thymosin Beta-4, a 43-amino-acid peptide produced by the thymus gland and found in high concentrations in wound healing tissue, platelets, and other cells involved in repair
