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Key ingredients: Glutathione, vitamin C, arbutin, and tranexamic acid
Amputation only BPC 157 (10 g/kg, 10 ng/kg), L-NAME (5 mg/kg), L-arginine (100 mg/kg), given alone or combined, were applied intraperitoneally, at 30 minutes before amputation while controls received simultaneously an equivolume of saline (5ml/kg intraperitoneally)
(Piscataway, NJ, USA), whereas TAT (YGRKKRRQRRR) control peptide was synthesized by Biomatik (Cambridge, Ontario, Canada)
revealed that Tan IIA exerts antifibrotic effects on cardiac fibroblasts and rat cardiac tissue by upregulating miR-618, thereby suppressing profibrotic factors (84)