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Importantly, the specificity of response to sera from patients with different CKD ( Figures 4J, K ), like focal segmental glomerulosclerosis (FGS), membranous nephropathy (MN), Alport syndrome (AS) and polycystic kidney disease (PKD) was tested, and the chip reacted similarly to human glomeruli in response to nephrotoxic serum and nephroprotective treatment, mirroring in vivo conditions

This fat-mobilising effect represents a metabolic action of HGH distinct from its growth-promoting IGF-1-mediated effects

Meanwhile, the values of the V max and k cat of pFeSAN were both higher than those of FeSAN