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Despite the continuous progress in radiation technology, which allows for more precise radiotherapy of local tumor tissues while reducing the effect on normal tissues, problems such as radioresistance and tumor recurrence remain major challenges in the application of radiation therapy (144)

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Given that acetyl-l-carnitine has a neuroprotective action shown in an animal model of ALS [85], it was hypothesised that treatment with acetyl-l-carnitine could help patients with ALS