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Researchers call this the "L-Arginine paradox" and attribute it to factors such as enzyme compartmentalization, the role of endogenous inhibitors (such as ADMA), and individual variation in amino acid metabolism

GLS is an enzyme that converts glutamine to glutamate, and small molecule inhibitors targeting GLS include CB-839, 968 and BPTES

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

Journal of cardiovascular electrophysiology

Muscle Growth and Preservation Increased GH and IGF-1 levels stimulate protein synthesis, promoting muscle hypertrophy and reducing muscle catabolism