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106 De novo mutations in the autism-related chromatin modifier CHD8 are well studied, 88,270 with multiple de novo, truncating, or missense mutations observed in ASD patients

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So when patients switch from smoking to e-cigs or quit marijuana, youd expect to see increased levels of some antipsychotics and antidepressants (Anderson GD et al, Clin Pharmacokinet 2016;55:13531358)

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