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Specifically, TMPRSS2 processes the SARS-CoV-2 S-protein and enables the viral entry into host cells within 100-fold during infections and clinical conditions such as sepsis, renal ischemia-reperfusion injury and acute lung injury (ALI) 464

As with most biomedical treatments, it is most effective when administered under the supervision of an experienced physician

It is not a dietary supplement, antioxidant formulation, or medication

An effective gene-agnostic treatment like NPI-001 has the potential to work alone or in concert with gene therapies to improve patient outcomes

Clinical evidence (see Table 1 ) and meta-analyses (30) show a significant association between schizophrenia and a history of infection with various pathogens (for example, Chlamydophila psittaci , Chlamydia pneumoniae , Human Herpesvirus 2, Borna disease virus, and Human Endogenous Retrovirus W)