Alpha-tocopherol: roles in prevention and therapy of human disease
Inadequate intake of foods rich in glutathione precursors such as fruits, vegetables (particularly spinach, avocados, and asparagus), and certain meats can lead to lower glutathione levels
This pentadecapeptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) demonstrates remarkable physicochemical stability across diverse biological environments, including resistance to gastric acid degradation and enzymatic hydrolysis, which facilitates multiple routes of administration including enteral delivery
Plasma PGA levels, reflecting glutathione (GSH) metabolic homeostasis, were analysed in three groups represented by: healthy controls with the wild-type TTR genotype, asymptomatic carriers of the TTR-V30M mutation, and symptomatic patients with TTR-V30M amyloidosis
BioMed Pharmacother (2006) 60(3):97108