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Nicotine negatively affects the cardiovascular system (increasing heart rate and blood pressure and the risk of heart attack and stroke), respiratory/lung functioning (including inflammation, asthma and wheezing) and reproductive organs

Lindblom, What Is Appropriate for the Protection of the Public Health Under the U.S

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It is therefore essential that new public health interventions, such as cigarette-stick warnings, include messages that appeal to this vulnerable age group