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Modifications in GPX3 play a role in the regulation of various signaling pathways in cancer, including nuclear factor -B (NF-B), Wnt/-catenin and JNK signaling

We have a lead compound that we really want to explore, because it does, in fact, interact with a viral protein in the way that we predicted it to interact, so it has a chance of inhibiting viral entry into a host cell, says Brad Pentelute, an MIT associate professor of chemistry, who is leading the research team

DILI often mimics acute viral liver infections and lacks skin symptoms, making diagnosis challenging