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These findings should be overseen with glutamate as the major excitatory neurotransmitter in the central nervous system (i.e., cognitive functions such as learning and memory in the brain [200], the precursor of major inhibitory neurotransmitter GABA) but excitotoxic neuronal death as a direct result of high concentrations [201], and tight physiologic range that should be maintained [59]

Mice C57 female mice (8-week-old, weighing 1719 g) were purchased from SPF (Beijing, China) Biotechnology Co., Ltd

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This extended urinary detection suggests continued metabolism of tissue-bound peptide or slow release from tissue reservoirs

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