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By inhibiting NNMT, 5-Amino-1MQ: Reduces 1-methylnicotinamide production Preserves intracellular nicotinamide levels Increases NAD+ availability Shifts cellular metabolism toward oxidative pathways Enhances mitochondrial function and energy expenditure Decreases fat storage and adipocyte differentiation These effects support improved metabolic efficiency, reduced adipose tissue accumulation, and preservation of lean mass

Research has found that by week 24, patients taking the higher doses of Mounjaro (10 mg and 15 mg) can lose, on average, close to 15% of their starting body weight

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