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They found instead that the TIP peptide delivered directly to the kidneys not only reduced inflammation but actually decreased blood pressure, even in the face of a high-salt diet, and without interfering with the infection-fighting role of TNF

Kong D, Xu J, Zhang Q, Luo D, Lv Q, Li S, et al

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The pudendal nerve follows a tortuous path through the pelvic floor and girdle, leaving it vulnerable to compression and tension injuries at various points along its path

doi: 10.1186/s12934-016-0428-4 184 TangW.ZhangS.TanH.ZhaoZ