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ALSPAC-the Avon Longitudinal Study of Parents and Children

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while blood samples can be used to examine nicotine and its metabolites, the time course of nicotine metabolism in rodents limits the accuracy of detection with exposure across a self-administration session duration (e.g., 1+ hour)

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[*] In other words, when a tax increase became effective midyear, we plotted the higher rate for that year