Importantly, at study completion, 5A-1MQ-treated mice had a lower fat mass than the obese WD controls and their vehicle-treated counterparts and were not significantly different (with FDR correction) from the LD control mice (Fig
Sleep quality at these doses is often significantly better than at treatment initiation because substantial weight loss has occurred, potentially resolving sleep apnea and reducing the mechanical factors that interfere with breathing and comfort during sleep
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