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The GGCT family is subdivided into three groups: plant-specific GGCT (psGGCT), -glutamylamine cyclotransferases (GGACT), and the ChaC-like family proteins (Kumar et al., 2015)

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Whether this potential mechanism reflects glial or neuronal co-transmission is presently unclear, but potential VMAT2-dependent Put-GABA synthesis and release by monoaminergic neurons under extended waking/high nitrogen conditions is a particularly exciting possibility