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Compared with subcutaneous injections, gluteal IM injections can accommodate larger volumes of medication and are often used for drugs that require deep muscle delivery or slow absorption

For most patients, B12 injections do not cause any significant long-term health concerns

Refrigerating the vial at 2C to 8C (36F to 46F) drastically slows down the potential proliferation of any microorganisms that may have been introduced

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No finished-drug approval, no active IND, and no FDA-registered human clinical trials as of April 2026