Chen H, Lu C, Liu H, Wang M, Zhao H, Yan Y, et al
Conclusion By interrupting the degradation pathways of l-cysteine, serine and GSH and blocking glycogen formation, the GSH production efficiency was significantly improved
Injections of glutathione may alter the body's immune system and lead to severe skin reactions like Steven Johnson's syndrome
The concentration of total GSH was calculated by interpolating the absorbance of the samples on a calibration curve with known concentrations of 0, 1, 5, 10, 15, 20, 40, and 50 mol/L (prepared from a stock solution of 1 mM GSH)
Taken together with the clinical timeline, dechallenge response, and exclusion of alternative causes, these findings indicate that moxifloxacin best fulfills the criteria for the principal offending drug in this case (complete itemized scores and supporting evidence are provided in Supplementary Tables 3, S4 )