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For persistent or severe symptoms Any side effect that worsens over time, spreads beyond the application area, or is accompanied by systemic symptoms like fever, malaise, or swollen lymph nodes requires professional evaluation

Keep the vials in a small insulated cooler pack with a cold pack, but do not let them freeze

The gap between the volume of anecdote and the volume of human evidence is real

10 Pennypacker LC, Allen RH, Kelly JP, Matthews LM, Grigsby J, Kaye K, et al

For instance, a study employing mass spectrometry imaging found significant differences in metabolite distribution in the cerebellar cortex, prefrontal cortex, and hippocampus of depression model mice