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49 This was observed concurrently with a decrease in intracellular GSH and ratified that the mechanism of redox change caused by acrolein is probably via cellular GSH consumption in oral epithelial cells as well (Figure 1)

Although the mechanisms are not altogether known, it appears that extremely low testosterone levels may confuse the hypothalamus into misinterpreting temperature signals from the body, and overreacting to what it perceives as overheating