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Biochem Biophys Res Commun (2007) 360:43740

Fresh normal mucosal tissues, either utilized for human organoid culture or immersed in a 4% paraformaldehyde solution for immunofluorescence assay (IFA), were obtained from healthy regions of the intestinal tissue adjacent to the polyps, as identified and assessed by the physician during the tissue acquisition process

Figure 3 3.4 Cystine disrupts cellular redox homeostasis by regulating GSH/GSSG Glutathione, the most abundant intracellular thiol-containing compound, plays a critical role in cell defense against oxidative stress and various other cellular processes

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