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However, about 10-15% of acetaminophen is metabolized by CYP2E1 into a toxic metabolite known as NAPQI (N-acetyl-p-benzoquinone imine).[ref] Detoxification with glutathione: NAPQI then needs to be neutralized with glutathione, which is catalyzed using the GST genes

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It can dry your skin out even more, so use it less often and use lots of lotion

7 Finally, because warfarin is highly protein-bound, displacement interactions can enhance warfarins effects until equilibrium with serum concentrations can be reestablished