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The consequent ROS accumulation in the body is inevitably associated with tissue injury [1], since ROS are known to damage cell components, particularly DNA, leading to loss of function, induction of apoptosis, or even carcinogenesis [2]

The early studies of Golse et al

If the liquid remains cloudy, exhibits a yellow tint, or contains visible floating debris after 30 minutes, this indicates potential contamination or a compromised peptide structure

The recombinant AAVs were produced and packaged by the AAV Core Facility of Academia Sinica (Grant AS-CFII112-204)