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Nevertheless, analysis of the mass isotopomer contribution of U- 13 C glucose to -GC and GSH showed that the levels of M + 2-labeled [ 13 C] --GC and M + 2- and M + 4-labeled [ 13 C]-GSH were reduced in shACTL6A-expressing cells (Fig

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Therapeutic strategies targeting selective autophagy, such as AMPK activators and natural compounds, have shown promise in restoring mitochondrial homeostasis and alleviating cognitive deficits in diabetic animal models

US Food and Drug Administration, Center for Drug Evaluation and Research