Although these mechanistic studies elucidate the catalytic role of key active site residues, the basis of substrate specificity for the nucleophilic amino acid in the plant GS is less well understood
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Instead, they reserve it for those at high risk of rabies exposure, such as laboratory staff working with the virus that causes the disease, veterinarians, and people likely to receive animal bites
Boosting folate in these individuals may be necessary for a variety of reasons