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These compositional shifts are accompanied by elevated levels of uremic toxins (IS, PCS, indole, and p-cresol) and secondary bile acids derived from aromatic amino acid degradation and microbial secondary bile acid biosynthesis ( Table 1 ) [110]

R.HartfordC.SrinivasanA.LaverJ.et al (2013)

Similar content being viewed by others Introduction Trace element iodine is an essential component of the thyroid hormones triiodothyronine (T3) and thyroxine (T4), which promote basal metabolism, lipid metabolism, and protein synthesis

And this includes the immune system

Lin KM, Yang MD, Tsai CW, Chang WS, Hsiao CL, Jeng LB, Yueh TC, Lee MC, Bau DT