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Here are the best vitamin B12 injection sites for each method: Subcutaneous B12 injection sites Usually, the best places to give yourself a B12 shot subcutaneously are the abdomen, thigh, and upper arm, as you can see in this illustration: Although not shown above, the buttock is another good site for B12 shots

Plain sterile water (water for injection, WFI) contains no preservative

So, there is no one-size-fits-all answer

Patients who are truly deficient receive the treatment they need including injections when clinically warranted and patients who are not deficient are guided toward more appropriate solutions

This analysis gives researchers confidence in their data and supports reproducibility required for publications and peer review