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Although the robust innate immune response triggered by bacteria and their products can transiently enhance antitumor immunity, excessive or uncontrolled activation may lead to high levels of proinflammatory cytokines, cytokine release syndrome (CRS), or sepsis-like symptoms, with significant interindividual variability

The researchers believe that the phenomenon theyve observed can be linked to testosterones effect of increasing confidence in humans

10.1089/ars.2005.7.256 28 DaviesK

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There have been isolated case reports of liver injury with berberine use