SormaniMPMuraroPASchiavettiISignoriALaroniAet al
It is prepared by a U.S.-registered compounding pharmacy for individual patients based on a valid prescription, and its components are classified by the FDA as bulk drug substances under section 503A of the Federal Food, Drug, and Cosmetic Act
For maintenance, those with pernicious anaemia may need injections for life, while others might transition to a less frequent schedule or use tablets if the deficiency is diet-related
For most healthy individuals, clinical assessment and subjective response monitoring provide adequate oversight without laboratory testing requirements
Symptoms of B12 deficiency include fatigue, weakness, constipation, loss of appetite, and nerve problems such as numbness and tingling in the hands and feet