Plusieurs essais cliniques ont effectivement observ une baisse modeste de l'indice de mlanine aprs supplmentation orale, mais ces rsultats restent fragiles : chantillons rduits, htrognit des formes et des dosages, effets limits certaines zones cutanes
Environ Toxicol 29(10):11551161 Saleh DO et al (2024) Eugenol alleviates acrylamide-induced rat testicular toxicity by modulating AMPK/p-AKT/mTOR signaling pathway and bloodtestis barrier remodeling Scientific Reports, 14(1):1910 Zirkin BR, Papadopoulos V (2018) Leydig cells: formation, function, and regulation
The IL-1, IL-6, and TNF cytokine triad was found to be associated with PACS and create self-sustaining feedback in pro-inflammatory macrophages (Schulthei et al., 2022)
More large-scale clinical trials and studies are needed to confirm or deny the possible benefits of taking BPC-157
17 Alternatively, surgery to remove the prolactin-secreting tumor (a non-cancerous tumor in the pituitary gland) has also been shown to successfully lead to remission